Toxicology

A worldwide yearly survey of new data and trends in adverse by J.K. Aronson (Eds.)

By J.K. Aronson (Eds.)

The uncomfortable side effects of gear Annual used to be first released in 1977. it's been constantly released because then, as a every year replace to the voluminous encyclopedia Meyler's unwanted side effects of gear. each one new Annual maintains to supply clinicians and clinical investigators with a competent and significant every year survey of recent facts and traits within the quarter of difficult Drug Reactions and Interactions. a world workforce of experts has contributed to the informative, through severely studying it, and by way of pointing to no matter what is deceptive. offers a serious every year survey of latest facts and developments within the unwanted effects of substances. each one drug article comprises case histories. comprises exact info on drug-drug interactions.

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Dextroamphetamine causes a 6. 7. 8. 9. 10. change in regional brain activity in vivo during cognitive tasks: an fMRI study utilizing BOLD. Biol Psychiatry 2004;56:284–91. Bell EC, Willson MC, Wilman AH, Dave S, Asghar SJ, Silverstone PH. Lithium and valproate attenuate dextroamphetamine-induced changes in brain activation. Hum Psychopharmacol 2005;20:87–96. Silverstone PH, O’Donnell T, Ulrich M, Asghar S, Hanstock CC. Dextroamphetamine increases phosphoinositol cycle activity in volunteers: an MRS study.

Although slightly different dosages were used in the two groups, making a comparison of low dosages inappropriate, nevertheless at a dose of 5 mg/day there was a clear difference in plasma concentrations. Considering the potential use of donepezil in peoples with Down’s syndrome (67cr , 68c ) and the serious adverse effects of donepezil in these patients (69c ), this difference in pharmacokinetics of donepezil is important. The authors proposed that the usual maintenance dose of 10 mg/day in the USA and EU is probably too much for patients with Down’s syndrome; they recommended 3–5 mg/day instead.

17. 18. 19. 20. 21. Chapter 1 ated with methamphetamine use. J Emerg Med 2005;28:165–7. Assael LA. Methamphetamine: an epidemic of oral health neglect, loss of access to care, abuse and violence. J Oral Maxillofac Surg 2005;63:1253–4. Ohgake S, Hashimoto K, Shimizu E, Koizumi H, Okamura N, Koike K, Matsuzawa D, Sekine Y, Inada T, Ozaki N, Iwata N, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Shirayama Y, Iyo M. Functional polymorphism of the NQO2 gene is associated with methamphetamine psychosis.

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