Toxicology

Adverse Drug Interactions - A Handbook for Prescribers by George Stouffer

By George Stouffer

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Anticancer and immunomodulating drugs Other immunomodulating drugs triamcinolone see corticosteroids 367–374 see potassiumsparing diuretics and aldosterone antagonists 112–115 264, 268 2. Drugs acting on the nervous system 676 13. Metabolic drugs see antipsychotics 251–263 see antimuscarinics 240–247 triamterene triazolam trientine trifluoperazine trihexyphenidyl Anxiolytics and hypnotics Trientine Subcategory (drug groups only) Benzodiazepines trilostane 458 6. Other endocrine drugs Trilostane trimethoprim 542, 544, 545 10.

Drugs to treat infections Antibiotics Macrolides telmisartan see angiotensinII receptor antagonists 34, 35, 26, 27, 38, 39, 41, 42, 43, 44, 46, 48, 49, 51, 52 266 2. Drugs acting on the nervous system 339 3. Anticancer and immunomodulating drugs Anxiolytics and hypnotics Benzodiazepines temazepam temoporfin tenecteplase tenofovir tenoxicam liv see thrombolytics 401–402 605, 606, 10. Drugs to treat 608, 609, infections 610 see nonsteroidal antiinflammatory drugs (NSAIDs) 462–470 Subcategory (drug groups only) Cytotoxics Antivirals – antiretrovirals terazosin see alpha blockers 34, 35, 47, 48, 50, 51 terbinafine 579 10.

E. what the human body does to the drug). It relates to the effects that occur during absorption (which can also be adjusted by manipulating certain pharmaceutical properties), distribution, metabolism and excretion. Pharmacokinetic interactions result in changes in the concentration of the drug at its site of action. Absorption can be affected by changes to the transport proteins in the intestine (see the section on ‘Transport proteins’ below), due to drugs binding (chelating) with other drugs in the gut lumen, alterations of pH within the gut (particularly within the stomach) or alterations in gastrointestinal motility.

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