Anaerobic Infections: Diagnosis and Management by Itzhak Brook

By Itzhak Brook

With new infectious brokers, antibiotics, and situations of antimicrobial resistance always at the horizon, this box is an ever becoming self-discipline that calls for consistent vigilance. This booklet responds to burgeoning progress within the box and offers a complete and professional armamentarium of directions for the remedy and analysis of the complete breadth of grownup and pediatric anaerobic infections.

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The ability of colonic flora to interfere with the establishment of pathogens is termed “colonization resistance” (29). Antibiotics effective against anaerobes increase the gut population and subsequently the potentials for translocation of Enterobacteriaceae (30). Numerous studies utilized selective gut decontamination in an attempt to eradicate only the Enterobacteriaceae and preserve the anaerobes by using antimicrobials that are only effective against Enterobacteriaceae (31). The subjects of these studies were generally immunosupressed individuals and those prone to infections.

The role of beta-lactamase-producing bacterial in the persistence of streptococcal tonsillar infection. Rev Infect Dis 1984; 6:601–7. 16. Brook I, Gober AE. Emergence of beta-lactamase-producing aerobic and anaerobic bacteria in the oropharynx of children following penicillin chemotherapy. Clin Pediatr 1984; 23:338–41. 17. Brook I, Barrett CT, Brinkman CR, III, Martin WJ, Finegold SM. Aerobic and anaerobic bacterial flora of the maternal cervix and newborn gastric fluid and conjunctiva: a prospective study.

Effect of Iron Supplements The iron content of the formula influences the number of Clostridium spp. in the large intestine of infants (57). Clostridium tertium is more often isolated from breast-fed infants than from either group of bottle-fed infants, and Clostridium butyricum is more frequently recovered from infants bottle fed with iron supplement than from breast-fed infants or infants bottle fed without iron supplement. Enhancement of bacterial growth by iron has been recognized for some Clostridium spp.

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